Opportunity Information: Apply for CDC RFA JG 25 0072

The Centers for Disease Control and Prevention (CDC), through its Global Health Center and under PEPFAR, is offering a cooperative agreement opportunity titled "Strengthening the organizational capacity of the Ministry of Health to deliver a sustainable and resilient response to HIV/TB and related public health threats in the Kingdom of Eswatini." The focus is not on directly delivering clinical services, but on providing hands-on technical assistance to Eswatini's Ministry of Health (MOH) so it can more effectively plan, coordinate, and manage a long-term HIV and TB response that can also adapt to other emerging public health challenges. The overarching idea is to strengthen the "core operating system" of the MOH so the national response is better led, better financed, and better staffed over time.

Funding is structured as a cooperative agreement, meaning the CDC is expected to have substantial involvement in the work rather than acting only as a pass-through funder. The opportunity lists an Award Ceiling for Year 1 as 0 (none), while also indicating an anticipated approximate total funding amount of $2,000,000 for Year 1, contingent on the availability of funds. CDC expects to make 2 awards. The notice was created on 2024-12-17, and the original application closing date is 2025-03-05. The assistance is categorized under Health (CFDA 93.067).

The work is centered on building organizational capacity in three main domains. The first is leadership and governance, where applicants are expected to help strengthen MOH governance structures, oversight functions, and operational processes so the Ministry can credibly lead and coordinate the strategic objectives of the national HIV response. In practical terms, this implies support for clearer decision-making structures, stronger accountability and oversight routines, better coordination across departments and partners, and more reliable internal processes that translate national strategies into operational plans that are actually implemented.

The second domain is resource mobilization and financial management. The CDC is looking for evidence-based support that improves how the MOH attracts, manages, and uses resources for the HIV response. This includes strengthening financing approaches and stewardship mechanisms, increasing the visibility of the HIV response within government and among partners, and improving stakeholder engagement so that funding and in-kind support are better aligned with national priorities. The emphasis is on making financing more sustainable and transparent, reducing fragmentation, and ensuring that resources are directed toward the highest-impact activities.

The third domain is workforce planning and performance management. The opportunity calls for technical assistance to help foster a responsive health sector workforce that is coordinated, trained, and equipped to deliver on HIV/TB priorities. This is expected to be data-driven, meaning workforce decisions should be informed by credible staffing and workload data, service delivery needs, and performance information. The goal is to strengthen planning for staffing levels and skills, improve how performance is tracked and supported, and build systems that help the workforce adapt as program needs change.

Across all three areas, CDC stresses the use of evidence-based approaches and positions this investment as a way to improve resilience. By strengthening leadership, financing and stewardship, and workforce systems, the MOH should be better able to adjust quickly to shifts in the HIV/TB landscape, address implementation bottlenecks, and respond to related public health threats without having to rely on ad hoc structures or short-term fixes.

Eligibility is broad and includes state, county, city/township, and special district governments; independent school districts; public and private institutions of higher education; federally recognized tribal governments and other tribal organizations; public housing authorities; nonprofits with and without 501(c)(3) status; for-profit organizations (including those other than small businesses); small businesses; and unrestricted applicants. The funding opportunity number is CDC RFA JG 25 0072, and the issuing agency is Centers for Disease Control-GHC.

  • The Centers for Disease Control-GHC in the health sector is offering a public funding opportunity titled "Strengthening the organizational capacity of the Ministry of Health to deliver a sustainable and resilient response to HIV/TB and related public health threats in the Kingdom of Eswatini under PEPFAR" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
  • This funding opportunity was created on 2024-12-17.
  • Applicants must submit their applications by 2025-03-05. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 2 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Unrestricted.
Apply for CDC RFA JG 25 0072

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Frequently Asked Questions (FAQ)

What is the title of this CDC funding opportunity?

The cooperative agreement opportunity is titled "Strengthening the organizational capacity of the Ministry of Health to deliver a sustainable and resilient response to HIV/TB and related public health threats in the Kingdom of Eswatini."

Which CDC office is offering this opportunity?

The opportunity is offered by the Centers for Disease Control and Prevention (CDC) through its Global Health Center (GHC) and under PEPFAR.

What is the funding opportunity number?

The funding opportunity number is CDC RFA JG 25 0072.

What type of award is this?

This is a cooperative agreement, which means CDC is expected to have substantial involvement in the work rather than serving only as a pass-through funder.

What is the main purpose of the award?

The main purpose is to provide hands-on technical assistance to Eswatini's Ministry of Health (MOH) to strengthen its ability to plan, coordinate, and manage a long-term HIV and TB response that can also adapt to other public health challenges.

Is this opportunity intended to fund direct clinical service delivery?

No. The focus is not on directly delivering clinical services. The focus is on strengthening the MOH's organizational capacity (its "core operating system") so it can lead and sustain the national HIV/TB response over time.

Where is the work focused geographically?

The work is focused in the Kingdom of Eswatini, supporting the Ministry of Health.

What are the main technical domains this award is intended to support?

The opportunity is centered on three domains: (1) leadership and governance, (2) resource mobilization and financial management, and (3) workforce planning and performance management.

What kinds of activities fall under the leadership and governance domain?

Leadership and governance support is intended to strengthen MOH governance structures, oversight functions, and operational processes so the Ministry can credibly lead and coordinate the strategic objectives of the national HIV response. This includes improving decision-making structures, accountability and oversight routines, coordination across departments and partners, and internal processes that translate national strategies into operational plans that are implemented.

What kinds of activities fall under resource mobilization and financial management?

This domain emphasizes evidence-based support to improve how the MOH attracts, manages, and uses resources for the HIV response. It includes strengthening financing approaches and stewardship mechanisms, increasing the visibility of the HIV response within government and among partners, improving stakeholder engagement, reducing fragmentation, improving transparency, and aligning financial and in-kind support with national priorities.

What kinds of activities fall under workforce planning and performance management?

This domain focuses on technical assistance to help build a responsive health sector workforce that is coordinated, trained, and equipped for HIV/TB priorities. The approach is expected to be data-driven, using staffing and workload data, service delivery needs, and performance information to strengthen planning for staffing levels and skills, improve performance tracking and support, and build systems that can adapt as program needs change.

How does CDC describe the overarching strategy of this investment?

CDC frames the investment as strengthening the MOH's core operating system so the national HIV/TB response is better led, better financed, and better staffed, and can adapt to emerging public health threats without relying on ad hoc structures or short-term fixes.

What does "resilience" mean in the context of this opportunity?

Resilience refers to improving the MOH's ability to adjust quickly to shifts in the HIV/TB landscape, address implementation bottlenecks, and respond to related public health threats by strengthening leadership, financing and stewardship, and workforce systems.

What is the anticipated funding amount for Year 1?

The opportunity indicates an anticipated approximate total funding amount of $2,000,000 for Year 1, contingent on the availability of funds.

Why does the notice show an Award Ceiling for Year 1 as 0 (none)?

The notice lists an Award Ceiling for Year 1 as 0 (none) while also stating an anticipated approximate total funding amount of $2,000,000 for Year 1 (contingent on funds). The provided information includes both figures, but it does not explain the reason for the "0" ceiling.

How many awards does CDC expect to make?

CDC expects to make 2 awards.

What is the application closing date?

The original application closing date is 2025-03-05.

When was this notice created?

The notice was created on 2024-12-17.

What is the assistance listing / CFDA number and category?

The assistance is categorized under Health with CFDA 93.067.

Who is eligible to apply?

Eligibility is broad and includes: state, county, city/township, and special district governments; independent school districts; public and private institutions of higher education; federally recognized tribal governments and other tribal organizations; public housing authorities; nonprofits with and without 501(c)(3) status; for-profit organizations (including those other than small businesses); small businesses; and unrestricted applicants.

Are for-profit organizations eligible?

Yes. For-profit organizations (including those other than small businesses) are listed as eligible, and small businesses are also listed as eligible.

Are nonprofits required to have 501(c)(3) status to be eligible?

No. The eligibility list includes nonprofits with and without 501(c)(3) status.

Does the opportunity restrict applicants to certain organization types only?

No. The eligibility list is expansive and also mentions "unrestricted applicants," alongside many specific government, education, tribal, nonprofit, housing authority, and for-profit categories.

What is CDC expecting from applicants in terms of approach?

CDC stresses the use of evidence-based approaches across leadership and governance, resource mobilization and financial management, and workforce planning and performance management.

Is the expected work primarily about national-level systems rather than individual facilities?

Based on the description provided, the emphasis is on strengthening MOH structures, processes, financing stewardship, and workforce systems that support the national HIV/TB response and coordination, rather than running facility-level clinical services.

What public health areas are explicitly mentioned?

HIV and TB are explicitly mentioned, along with "related public health threats" and emerging public health challenges that the MOH should be able to respond to over time.

What does "hands-on technical assistance" imply in this context?

In the context provided, it implies practical support to strengthen governance, operational processes, financing and stewardship, stakeholder engagement, and workforce planning and performance systems so the MOH can better implement national strategies and manage the HIV/TB response sustainably.

Who is the primary partner or beneficiary of the technical assistance?

The primary partner/beneficiary described is Eswatini's Ministry of Health (MOH).

What does CDC mean by strengthening the MOH's "core operating system"?

It refers to strengthening the foundational organizational functions that help the MOH lead effectively over time: leadership and governance mechanisms, financing/resource mobilization and stewardship, and workforce planning and performance management systems.

Is Year 1 funding guaranteed?

No. The anticipated Year 1 funding amount is stated as contingent on the availability of funds.

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