Opportunity Information: Apply for 72067422RFA00009

The Accelerate TB Elimination and Program Resilience Activity (ACCELERATE 1) is a USAID/South Africa funding opportunity designed to strengthen South Africa's tuberculosis (TB) response by providing high-level technical support and targeted interventions where TB burden is most intense. It is positioned as part of USAID/SA's flagship TB effort called ACCELERATE, which is structured as two separate activities, with ACCELERATE 1 specifically focused on national-to-district technical assistance and practical program interventions that help push the country toward TB elimination while also improving the resilience of the broader health system.

This opportunity was released by the U.S. Agency for International Development (USAID), South Africa mission (USAID-Pretoria), under Funding Opportunity Number 72067422RFA00009. It falls under the discretionary funding category and uses a Cooperative Agreement as the funding instrument, which typically means USAID expects substantial involvement during implementation (for example, alignment on workplans, monitoring expectations, and iterative program adjustments). The activity is classified within the health funding category and is associated with CFDA number 98.001. The solicitation was created on September 21, 2022, with an original closing date of November 21, 2022. USAID anticipated making a single award, with an award ceiling of USD 47,000,000, indicating a large, centralized implementing partner model intended to operate across multiple levels of the health system and multiple geographies.

Programmatically, ACCELERATE 1 is built around two major aims. First, it seeks to deliver targeted technical support at the national level and tailored technical support at provincial and district levels, especially within communities and healthcare facilities located in high TB burden areas. The geographic focus is explicit and concentrated in three provinces and specific high-burden districts: Gauteng (Tshwane and Sedibeng), KwaZulu-Natal (Uthukela and Amajuba), and Eastern Cape (Nelson Mandela Bay, Joe Gqabi, and Sarah Baartman). This suggests the activity is meant to translate national TB policy, strategy, and best practices into operational improvements in priority districts, while also ensuring that lessons and data from districts inform national decision-making and refinement of TB approaches.

Second, the activity emphasizes strengthening health systems at national, provincial, and district levels while advancing TB elimination in a way that sustainably improves public health service delivery. In practical terms, this kind of framing usually points to strengthening core system functions that TB programs rely on, such as planning and coordination, surveillance and data quality, monitoring and evaluation, laboratory and diagnostic networks, referral systems, supply chain reliability for TB commodities, and quality improvement in clinical and community service delivery. The inclusion of "program resilience" and explicit mention of mitigating the negative impacts of acute infectious disease epidemics signals that the activity is also meant to help the TB program and underlying health services withstand shocks like outbreaks that disrupt routine care, staffing, budgets, and patient access. The overall intent is not only to improve TB outcomes in the short term, but to leave behind stronger, more adaptable systems that can maintain essential TB services and broader public health functions during periods of crisis.

Eligibility is listed as "Others," with additional eligibility details referenced in the full notice. That wording typically means eligibility may extend beyond standard categories (for example, potentially including nonprofit organizations, universities, consortia, or other qualified entities), but the definitive criteria would be in the full eligibility section of the solicitation. Overall, ACCELERATE 1 is a large-scale, single-award, cooperative agreement mechanism intended to accelerate progress toward South Africa's TB elimination goals by combining national-level technical leadership with hands-on, district-focused support in the highest-burden settings, while simultaneously reinforcing the resilience and continuity of the health system in the face of infectious disease threats.

  • The Agency for International Development, South Africa USAID-Pretoria in the health sector is offering a public funding opportunity titled "Accelerate TB Elimination & Program Resilience Activity (ACCELERATE 1)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 98.001.
  • This funding opportunity was created on Sep 21, 2022.
  • Applicants must submit their applications by Nov 21, 2022. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $47,000,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
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